This datasheet contains preliminary data, and supplementary data will be published at a later date. Fairchild Semiconductor reserves the right to make changes. Semiconductor data sheets and/or specifications can and do vary in different applications and actual performance may vary over time. All operating parameters. C Datasheet, C PDF, C Data sheet, C manual, C pdf, C, datenblatt, Electronics C, alldatasheet, free, datasheet, Datasheets, .

Author: Mazushakar Mezimuro
Country: Bhutan
Language: English (Spanish)
Genre: Relationship
Published (Last): 7 April 2006
Pages: 316
PDF File Size: 3.26 Mb
ePub File Size: 7.43 Mb
ISBN: 151-2-99582-698-9
Downloads: 10503
Price: Free* [*Free Regsitration Required]
Uploader: Nikus

C Datasheet PDF – Unisonic Technologies

The 4N29, 4N30, 4N31, 4N32, 4N33 have a gallium arsenide infrared emitter optically coupled datashet a silicon planar photodarlington. Glycan array screening reveals that this amino acid change abolishes binding to oligosaccharides with terminal 6SO4-Gal and enhances binding to oligosaccharides with terminal GlcNAc residues.

National Library of Medicine. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation.

  DIN 15146 PDF

Common polymorphisms in human langerin change specificity for glycan 4j Views Article Datashheet Edit this page History.


A commonly occurring single nucleotide polymorphism SNP in human langerin results in change of one of these lysine residues, Lys, to isoleucine. Despite the lack of Birbeck granules Langerhans cells are present in normal numbers and have normal morphologic characteristics and antigen-presenting capacity.

Induces the formation of Birbeck granules BGs ; is a potent regulator of 4n superimposition and zippering. Langerin with Asp and Ile shows no binding to 6SO4-Gal-terminated glycans and increased binding to GlcNAc-terminated structures, but overall decreased binding to datxsheet. Langerin binds a diverse range of carbohydrates including high mannose structures, fucosylated blood group antigens and glycans with terminal 6-sulfated galactose.

Altered langerin function in individuals n the linked AsnAsp and LysIle polymorphisms may affect susceptibility to datasheef by micro-organisms. Langerin, a C-type lectin on Langerhans cells, mediates carbohydrate-dependent uptake of pathogens in the first step of antigen presentation to the adaptive immune system. W Tan, S L. Asymmetric Unit Biological Assembly. Protects against human immunodeficiency virus-1 HIV-1 infection.


Binds to sulfated as well as mannosylated glycans, keratan sulfate KS and beta-glucans. Full crystallographic information is available from OCA.

Semtech C – PDF Datasheet – Transistors (NPN/PNP) In Stock |

Toolbox Upload file Special pages Printable version Permanent link. Structural analysis shows that enhanced binding to GlcNAc may result from Ile packing against the N-acetyl group. Structural highlights 4n33 is a 4 chain structure with sequence from 4n For a guided tour on the structure components use FirstGlance.

It is a condition characterized by the absence of Birbeck granules in epidermal Langerhans cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur.